Young women are now paying the price for drinking through breast cancer

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Teach your daughters not to drink alcohol

Some alarming results, recently reported in the Journal of the National Cancer Institute and in the Oxford Journals.

Women who drink the equivalent of one glass of wine a night through their teens and early twenties increase their chance of breast cancer by one third, according to new research.

Here are some points from the report:

Background Adult alcohol consumption during the previous year is related to breast cancer risk. Breast tissue is particularly susceptible to carcinogens between menarche (first period) and first full-term pregnancy. No study has characterized the contribution of alcohol consumption during this interval to risks of proliferative benign breast disease (BBD) and breast cancer.

Methods We used data from 91005 parous women in the Nurses’ Health Study II who had no cancer history, completed questions on early alcohol consumption in 1989, and were followed through June 30, 2009, to analyze breast cancer risk. A subset of 60093 women who had no history of BBD or cancer in 1991 and were followed through June 30, 2001, were included in the analysis of proliferative BBD. Relative risks (RRs) were estimated using Cox proportional hazard regression.

Results We identified 1609 breast cancer cases and 970 proliferative BBD cases confirmed by central histology review. Alcohol consumption between menarche and first pregnancy, adjusted for drinking after first pregnancy, was associated with risks of breast cancer (RR = 1.11 per 10g/day intake; 95% confidence interval [CI] = 1.00 to 1.23) and proliferative BBD (RR = 1.16 per 10g/day intake; 95% CI = 1.02 to 1.32). Drinking after first pregnancy had a similar risk for breast cancer (RR = 1.09 per 10g/day intake; 95% CI = 0.96 to 1.23) but not for BBD. The association between drinking before first pregnancy and breast neoplasia appeared to be stronger with longer menarche to first pregnancy intervals.

Conclusions Alcohol consumption before first pregnancy was consistently associated with increased risks of proliferative BBD and breast cancer.

Alcohol is considered by the International Agency for Research on Cancer to be causally related to invasive breast cancer (hereafter called “breast cancer”) (1), with a 7% to 10% increase in risk for each 10g alcohol consumed daily by adult women. One mechanism may be alcohol-induced increases in circulating estrogens and subsequently epithelial cell proliferation. However, the risk attributable to alcohol intake during adolescence and early adulthood remains inconclusive. (photo below

And here is the story in plain speak from the Telegraph.Uk:

The study published in the Journal of the National Cancer Institute found that mothers who had drunk around two units of alcohol a day (1 glass of wine) in the decade after their periods began were 34 per cent more likely to develop the disease than those who did not drink during the same period.

The association was strongest among mothers who started their family later in life.

Research has previously found that alcohol is a key factor in breast cancer, with women who drink around two units a day having about a 24 per cent increased risk of the disease.

The new study found that the risk was even more marked if women started drinking younger, with an even stronger association depending on how long they were fertile for before becoming pregnant.

Women who never have children, or delay becoming pregnant, were already known to be more susceptible to breast cancer.

Researchers led by Dr Ying Liu from Washington University School of Medicine in St Louis, US, examined the history of 91,000 women aged 15 to 40,

The evidence suggested that alcohol consumed before first pregnancy may play an important role in the development of breast cancer, said the researchers.

“Reducing alcohol consumption during this period may be an effective prevention strategy,” they concluded.

The findings indicated a dose-dependent relationship, which means the more alcohol a woman drinks during that time, the higher her risk of developing breast cancer.

Dr Liu said: “The general consistency in the patterns of association between alcohol and risk of proliferative benign breast cancer disease and of breast cancer lends support to the hypothesis that alcohol intake, particularly before first pregnancy when breast tissue is likely at its most vulnerable stage, may play an important role in the etiology of breast cancer.”

2 comentarii (+add yours?)

  1. Raveca
    sept. 05, 2013 @ 11:22:34

    Poate e adevarat,dar mama mea a avut breast cancer la 79 de ani si nu a baut o data ….Raveca…

    • rodi
      sept. 05, 2013 @ 12:02:46

      Draga Raveca,
      bautura nu este singurul motiv pentru ‘breast cancer’, dar pentru fete tinere care consuma alcool, riscul se ridica cu 30 % ca vor fi diagnisticate cu cancer la piept. Deci, o femeie care se fereste de alcool se ajuta pe sine sa isi minimalizeze riscul pentru aceasta boala.

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